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Gaining NHS Permission for clinical research

When research involving human participants (or their organs, tissue or data) is hosted in or through the NHS, written permission on behalf of the NHS organisation providing care must be in place before the research can begin.

The NIHR Coordinated System for gaining NHS Permission (CSP) standardises and streamlines the process of gaining NHS Permission for commercial and non-commercial clinical research studies in England.

Who can use CSP?

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Why use CSP?

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Overview of the CSP Process

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The following studies can use CSP:

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It is the recommended route for companies to gain NHS permission blue bar

It is the mechanism to access NHS service support for non-commercial studies eligible for the NIHR CRN Portfolio blue bar

It offers a single point of access, via the Integrated Research Application System (IRAS) blue bar

Support and advice is available from the Comprehensive Local Research Networks (CLRNs) blue bar

It provides an efficient process for gaining NHS Permission blue bar

Click on the image below to open an interactive flowchart describing the CSP process.

CSP flowchart

More about improvements

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Contact us

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Help and guidance

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Improvements update

If you would like to check on the progress of a specific study which is proceeding through CSP, please contact the Lead CLRN in the first instance.

If you have any questions about NIHR CSP, including how to access NIHR CSP through IRAS, or you would like to give any feedback or suggestions, contact the NIHR CSP Helpdesk.

E: crncc.csp@nihr.ac.uk
T: 0113 343 2314

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