The International Standard Randomised Controlled Trial Number (ISRCTN) is a simple numeric system for the unique identification of clinical trials worldwide. Please see the ISRCTN register website for more information. The Department of Health (DH) funds ISRCTN registration for eligible NIHR CRN Portfolio studies.
All studies eligible for Clinical Research Network support which have a UK CRN ID number are able to regsiter for an ISRCTN using the UK CRN Portfolio Database.
How to register
Log onto the Portfolio Database and select 'yes I wish to register for an ISRCTN' and complete the extended minimum dataset required for ISRCTN registration.
Which studies are eligible for free ISRCTN registration?
Non-commercial studies with an interventional component included on the NIHR Clinical Research Network (CRN) Portfolio qualify for ISRCTN regsitration funded by the DH in England. Please see the table below which defines the NIHR CRN Portfolio studies that will be eligible.
Free ISRCTN registration eligiblity crtieria for NIHR CRN Portfolio studies
Primary study design:
‘Both’ (i.e. interventional and observational)
In set up’
‘Closed - in follow up’
ISRCTN and ClinicalTrials.gov status:
NIHR CRN Portfolio study:
‘An NIHR non-commercial Partner’
‘NIHR CRN Portfolio adopted, non-commercial study’
Studies which may be registered with ISRCTN but are NOT eligible for free registration
We encourage ISRCTN registration on industry-supported industry sponsored, observational and devolved nations1 studies via the Portfolio Database. However, the DH will not fund the registration of these studies. If you choose to register we will flag this to Current Controlled Trials who will invoice the primary study Sponsor (as provided through CSP/during NIHR Clinical Research Network support eligiblity process) for the full registration fee.
For up to date details on the ISRCTN registration fee go to www.controlled-trials.com/isrctn/submission/.
1 Devolved nations studies are those studies included on the UK CRN Portfolio database that don't have English sites